Question
Gepost op: 29 März 2026What is the best approach for preparing a scalp lotion consisting of 3 g saponine coaltar, 0.5 g prednisolone, and water up to 100 g, considering that prednisolone is insoluble in water and the 3 g of alcohol-based saponine coaltar is likely insufficient to keep the prednisolone in solution upon dilution, and how does saponine coaltar behave when diluted with water?
Answer
Gepost op: 29 März 2026Preparation Method
Tare a beaker and a stirring rod (T g). Weigh 20 g of propylene glycol and dissolve the prednisolone in it. Then add the coal tar saponin and 15 g of Tween 80. Mix everything with the stirring rod until a homogeneous mixture is obtained. Place the beaker with the stirring rod on the balance and gradually add water, while stirring well, until a total weight of T + 100 g is reached.
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