Question
Gepost op: 29 März 2026How can 'SPORTFLEX spray' (indometacine) be reformulated into an oil-based preparation at the patient's request?
Answer
Gepost op: 29 März 2026Advice on Preparation
Providing an exact numerical value for this query is difficult. Using oil exclusively may result in a product that is too greasy. It is recommended to use 30% to 50% castor oil and dilute to 100% with ethanol.
Castor oil serves as a solvent for indomethacin and is itself soluble in ethanol. The exact solubility of indomethacin in this mixture is unknown, partly because the desired concentration of indomethacin has not been specified.
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