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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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What is a compounded alternative for Nizoral cream, which contains ketoconazole, given that it is no longer reimbursed as of November 1st?
An O/W cream contains 100 mg of prednisolone and rice starch; why does this cream contain rice starch, and can it be replaced by wheat starch?
How can a stable preparation of 300g of 30% urea in lipophilic cream be formulated for a patient requiring a fatty cream, given that using AVA as the lipophilic base resulted in the cream breaking within a month?
What is the best preservative to use for an eye drop preparation containing 250 mg zinc sulfate, boric acid q.s., and purified water up to 100 ml (dispense 10 ml), considering that Na2EDTA is incompatible due to zinc complexation, benzalkonium chloride is reportedly incompatible with sulfates according to Martindale, and phenylmercuric borate may be incompatible with metals?
Can lactose be used as a filler for tetracycline capsules?
Can a collyre containing 4% cocaine, 0.01% adrenaline tartrate, and 0.05% chlorobutanol be dissolved in a boric acid/borax buffer to achieve the correct pH, and can the prescribed adrenaline and chlorobutanol be added to this cocaine eye drop solution without encountering issues regarding pH or shelf life, given that a boric acid and borax buffer is used as a solvent for 4% cocaine eye drops in previously asked questions?
Is it possible to prepare a 10% acetylcysteine nasal spray?
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