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Die Rezeptur‑Helpdesk enthält mehr als 1500 Fragen und Antworten zu verschiedenen galenischen Themen, alle bereitgestellt von Prof. R. Kinget.
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Is an antioxidant necessary for the following preparation with resorcinol (R/ salicylic acid 1.1 g, resorcinol 2.2 g, alcohol 70 degrees AD 55 g), given that according to Martindale resorcinol is sensitive to oxidation (pink discoloration), and if so, should a water-soluble (vit C), fat-soluble (BHT), or both antioxidants be added?
How can Strattera (atomoxetine) capsules be processed into a syrup?
Can Redomex tablets and Baclofen powder be processed into capsules; and given that Redomex contains lactose and the specialty Baclofen also contains lactose, can lactose be used as a filler for the preparation of Redomex 20 mg and Baclofen 9 mg capsules, or if mannitol must be used, can Redomex be combined with Baclofen in capsules?
Magnesium dried 125 mg appears in a preparation. Which magnesium can I use for the following formula: ATP 30 mg, magnesium dried 125 mg, 30 enteric-coated capsules?
Can the sour taste of a citric acid/tripotassium citrate syrup be improved with raspberry extract, and what is the best way to prepare the formula provided by the nephrologist: 240g tripotassium citrate, 60g citric acid, 24ml citric acid spirit, 360ml water, and sugar syrup up to 1200ml?
How can a 25% sodium thiosulfate in zinc oxide ointment be prepared for an immunocompromised patient with calcinosis, considering that research by the Radboud MC pharmacy on a 10% sodium thiosulfate cream in cooling ointment indicates the substance oxidizes strongly into sulfur, sulfite, and sulfate, requiring processing under nitrogen—a capability the current pharmacy lacks—thus making it impossible to guarantee the required 90-110% content stability?
Regarding the ear drops consisting of 5 ml Ciloxan and 75 ml hydrocortison solution, is the dosage of 5 ml Ciloxan in 75 ml solution not too low, and what can be used for the hydrocortison solution?
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