How can a glossy o/w cream be formulated using 14.5% w/w white soft paraffin, 12.6% w/w light liquid paraffin, and 1% w/w hypoallergenic anhydrous lanolin (Medilan) to match E45 Cream, given that previous attempts with 3% Tween 80, 3% Lanette SX, and a combination of 1% white wax with 2% Tween 80 resulted in either breaking, excessive liquidity, or a white residue?

What is the cause for a preparation containing 15 mg tretinoin, 3.6 g denatured alcohol, 12 mg butylhydroxytoluene, 4% hydroquinone, and 0.5% hydrocortisone acetate in cetomacrogol cream up to 300 g having a shelf life of only about 14 days, and how can the formula be improved?

Given that Orthogynest Depot has been discontinued, what base should be used for a "loco" preparation, such as a mixture of PEG 4000 and PEG 1500/300, and in what ratio; how can a depot effect be achieved, perhaps by adding 2% Aerosil; is an additional preservative required; and can a 2 g suppository mold be used instead of an ovule mold, as it is the first time in 15 years of pharmaceutical practice that these ovules must be prepared?

How can a 2% iodine solution be prepared for drinking water disinfection starting from a 6.5% iodine tincture (Conforma) containing 6.5% iodine, 2.5% potassium iodide, and 90° ethanol up to 100% (m/m)?

What is the appropriate type and quantity of emulsifier to add, or what alternative method can be used, to resolve the incompatibility observed when adding a melted and cooled ointment base to Elocom lipophilic cream in a formula containing 100 g Elocom lipophilic cream, 12 g Lanette N, 12 g white wax, 10 g glycerol, 6 g Cetiol V, and water up to 300 g?

What is a suitable compounded alternative for phenylephrine 15% eye drops that has been unavailable for some time, how can the isotonicity be best adjusted, and what is the maximum shelf life after opening?

What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?