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La mesa de ayuda de formulación contiene más de 1500 preguntas y respuestas sobre diversos temas galénicos, todas proporcionadas por el Prof. R. Kinget.
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How should this magistral preparation for a lipstick be made, given that the received prescription contains 1.5 g Vitamin D2, 62 g cocoa butter, 5 g boric acid, and water up to 100 g (which suggests Aquaphil might have been intended), and considering that when the water and cocoa butter were heated and mixed they failed to combine, leading to the addition of Tween 80 until they mixed and the subsequent addition of boric acid, which did not dissolve well and resulted in a mixture that remained liquid after cooling and began to separate after standing?
How should the following hypertonic NaCl eye ointment with boric acid be prepared: NaCl 0.7g, H2O 1.5g, white vaseline 6.5g, and boric acid 10 mg, processed into a grain-free emulsion?
With which product could tragacanth be replaced in a prescription containing 25 mg prednisolone disodium sulfate, 12 drops of opium tincture, 0.8 g tragacanth, 12 g sulfaguanidine, 15 g 5-aminosalicylic acid, and aqua up to 300 cc, with instructions to administer a 40 ml enema in the evening?
Is it possible to successfully prepare an AVA cream with a fat phase of only 30% as requested by a dermatologist?
What are the molar masses of copper gluconate and zinc gluconate for a prescription of 1 mg copper and 15 mg zinc, and what is the required amount for selenium-methionine, which is also listed without a quantity?
In the preparation of a mouthwash containing 0.5g tetracycline HCl, 0.2g lidocaine HCl, 0.1g vitamin A acetate (500,000 UI/g), 0.5g hydrocortisone base, and 3% mint water up to 100 ml, where vitamin A oil is solubilized with Tween 80 (8:1) and mint is replaced by bitter orange peel tincture for flavor, will tetracycline and lidocaine remain in solution while hydrocortisone is suspended? If not, should tetracycline be precipitated for better efficacy at a higher pH, and how would this affect lidocaine's solubility; furthermore, is the addition of xanthan gum useful for stabilization and viscosity, and how should the preparation be preserved given that Tween inactivates parabens?
What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?
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