Question
Gepost op: 29 March 2026Regarding topical simvastatin, what is the best dermatological excipient for a 2% simvastatin formulation?
Answer
Gepost op: 29 March 2026Preparation Options
Recent literature suggests several options for this preparation:
- Simvastatin 2% in cholesterol cream or ointment. Eucerine cum aqua (1:1) can be used for this purpose.
- A second option is a composition consisting of: petrolatum 88 g, liquid paraffin 10 g, cholesterol 2 g, and 0.1% BHT.
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