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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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Given that chlorpheniramine maleate is missing from the list of maximum doses while dexchlorpheniramine maleate is included, should I use the maximum dose of the isomer dexchlorpheniramine maleate for chlorpheniramine maleate, or is such equivalence only permitted for different salt forms?
Is it necessary to use unbuffered cetomacrogol cream for a preparation containing triamcinolone acetonide, neomycin sulfate, and nystatin, and is it specifically required for one of these components or for triamcinolone itself?
How can 'SPORTFLEX spray' (indometacine) be reformulated into an oil-based preparation at the patient's request?
What is the cause of the problem during the enteric coating of 15 capsules containing 2.5 mg Levocetirizine Teva, 250 mg acetylsalicylic acid, 250 mg paracetamol, 5 mg caffeine, and 2 mg methylprednisolone, given that during the drying process a cracking sound is heard and the capsules appear to have disintegrated, while enteric coating empty capsules presents no such issues?
What is the cause of precipitation in a preparation where DMSO is used instead of Bonain's solution, given a composition of 2 g cocaine HCl, 2 g menthol, 2 g lidocaine base, 4 g DMSO, and approximately 1.5 g NaHCO3 to reach a pH of 6.5, and considering the process involved mixing solid components in a beaker, adding DMSO, measuring pH, adding NaHCO3, and allowing it to dissolve for 2 hours?
What is the capsaicin content in capsicum oleoresin, given that a preparation must be made using 1% capsicum extract (equivalent to 0.025% capsaicine) and only capsicum oleoresin is available?
What is the composition of Darier's base?
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