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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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2468 resultaten gevonden
Can buffered cetomacrogol cream be used for the preparation of amitriptyline 10% cream, and is there anything else that needs to be added?
For the following prescription: Nystatin 150,000 IU and Miconazole 300 mg for 20 vaginal ovules, should miconazole base be used as prescribed, or is the use of miconazole nitrate (similar to Gyno-Daktarin) also permitted?
How should an ear drop formula containing 180,000 UI oxytetracycline (or one bottle of Ciloxan if unavailable), 200,000 UI polymyxin B, 2,000,000 U nystatin, and 20 mg dexamethasone be prepared in 30 ml of water for use twice daily for three weeks, considering the lack of clarity regarding Ciloxan replacing only oxytetracycline, the poor solubility of nystatin and dexamethasone in water, and the limited three-week stability of an aqueous solution?
How should a pharmacist handle a regular preparation request for a combination of 2% resorcinol, 2% salicylic acid, and 4% erythromycin in 50% isopropanol, given that the dermatologist insists on this combination despite the incompatibility between salicylic acid and erythromycin?
How can a pharmacist prepare a solution containing 20 g benzocaine, 8 g tetracaine HCl, and water up to 100 g, based on an old formula called Novo Loco, given that the dentist requires a solution rather than a suspension despite benzocaine's low solubility in water (1/2500) and the high concentration requested?
What is the cause of precipitation and turbidity in a vitamin A solution (50,000 IU/ml) prepared with 5,000,000 IU synthetic vitamin A acetate oil (approx. 1,500,000 IU/g), 240 mg citric acid, 35 drops banana aroma, 300 mg potassium sorbate, 12.5 g Tween 80, 12.5 g simple syrup, and distilled water up to 100 ml, considering the solution remains clear immediately after preparation but develops glistening particles after five days in the refrigerator, even when using new batches of vitamin A and simple syrup?
What is the recommended alternative for preparing a testosterone propionate gel consisting of 2250 mg testosterone, 5 g oleic acid, 2% hydroxypropyl cellulose, and 94° ethanol up to 90 g, given that both oleic acid and the previously considered alternative Eutanol are currently unavailable?
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