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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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What is the correct procedure and stability for a preparation containing 1.5 g betaine, 40 drops of mint essence, 0.2 ml Tween, and water up to 300 ml, and is it permissible for the betaine to be in solution?
What is the ideal preparation method for a sterile ear drop solution containing 100 mg clioquinol and 10 mg triamcinolone acetonide in polyethylene glycol 400 up to 10 ml, and is sterilization necessary if the solubility of these components is limited and the application is intended only for the outer ear?
What is the recommended preparation method for a cream containing 45 g emulgent cetostearyl alcohol (Eumulgin C1000), 90 g glycerol, 153 g preservative rose water, 6 g dimethicone, and 6 g sodium lauryl sulfate (totaling 300 g), considering that the purchased rose water contains benzalkonium chloride and is incompatible with sodium lauryl sulfate, yet even without it, no cream is formed despite a similar rose-scented cream being used by the physician?
How can an ointment be prepared and used given that hexachlorophene is no longer available and dimethicone 500 is out of stock, for a formula consisting of 12 g dimethicone 500, 0.3 g rutin, 0.13 g hexachlorophene, 0.6 ml aqua, 15 g lanolin, and 29 g vaseline?
How can a highly hygroscopic powder, such as Ammonaps, be improved for filling into 250 mg capsules, given that the powder becomes sticky after just a few minutes of exposure to air?
How can a stable cream be prepared for a formulation containing 0.1% betamethasone valerate, 5% salicylic acid, and 5% Albychtiol in hydrated Eucerin up to 300 g, given that this specific combination currently results in an unstable product?
What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?
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