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De helpdesk bevat meer dan 1500 vragen en antwoorden over diverse galenische topics, allemaal aangeleverd door Prof. R. Kinget.
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What is the best base to use to obtain a stable preparation with salicylic acid and chlorhexidine, given that a green discoloration occurred in a cream containing 25 mg clobetasol dipropionate, 1.25 g chlorhexidine gluconate 20% solution, 2 g salicylic acid, and cetomacrogol cream up to 50 g, and that buffered cetomacrogol cream was used for the salicylic acid but appears to be incompatible with chlorhexidine?
Can eye drop formulations for Amphotericin 0.1%, prepared by dissolving powder in water and diluting with glucose, be used as ear drops, and can Ambisome be used for this purpose instead of Fungizone, which must be ordered from abroad?
Why do 2g suppositories containing 2mg ergotamine tartrate and 100mg caffeine from the TMF break easily when using Witepsol H15 with 2mg tartaric acid added per suppository, slow heating and cooling, and storage in the refrigerator, and would using a different base be recommended?
What is the composition for an aqueous solution of vitamin E for a 2-month-old baby, given a dosage of 75 IU/ml and a posology of 0.7 ml per day for 2 months?
How do I prepare a pyrazinamide suspension?
What could be the reason why hard gelatin capsules filled with aspirin burst when they are enterically coated, given that the uncoated part audibly cracks immediately after immersion in CAP?
What are the stability problems of a solution containing 3 grams of Phenobarbital sodium and purified water up to 300 cc?
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