Why does the following emulsion, containing 2% miconazole nitrate, 0.12% betamethasone valerate, 5% salicylic acid, 3% Lanette SX, 3% almond oil, and water up to 100 g, break?

Regarding topical simvastatin, what is the best dermatological excipient for a 2% simvastatin formulation?

What is the correct procedure for incorporating salicylic acid into a corticosteroid-containing ointment consisting of 0.05% clobetasol dipropionate, 30 g TMF hydrophobic ointment, 40 g Unguentum simplex, 10 g talc, 10 g zinc oxide, 2 g salicylic acid, and aqua dist. q.s., given that the physician specified adding water until saturation when asked about the total volume?

What is the recommended preparation method for a 20% gabapentin cream, given that a gynecologist claims it is possible to use cetomacrogol cream, but crystallization occurs at concentrations above 8%?

What can potassium sorbate be replaced with in glycopyrronium oral solution FNA, given that potassium sorbate is currently unavailable, for a preparation containing 20 mg glycopyrronium bromide, 50 mg saccharin sodium, 100 mg sorbic acid, 100 mg potassium sorbate, and 99.73 g purified water?

Is it possible to suspend microcrystalline progesterone in Liquifin to create an oral dosage form of 25 mg to 50 mg for hormone replacement therapy, given that the currently available 100 mg and 200 mg soft oil capsules provide too high a dose for the patient?

What is the recommended formula for administering Amikacine vaginally as a cream or ovule, considering Amikacine sulfate no longer seems to be available as a licensed raw material, and can an IV solution be used as a starting point or would its stability be insufficient?