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La mesa de ayuda de formulación contiene más de 1500 preguntas y respuestas sobre diversos temas galénicos, todas proporcionadas por el Prof. R. Kinget.
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Regarding the incompatibility in a mouthwash with the following prescription: 2g lidocaine hydrochloride, 8g propylene glycol, 4g hypromellose, 1.2ml flavoring, 120mg sodium saccharinate, and aqua conservans up to 400ml, is it necessary to add disodium phosphate dihydrate? If so, how much should be added, and is there a specific order of preparation that must be followed?
What is the recommended approach for preparing a solution containing 1 g of glycopyrrolate, 1 g of benzyl alcohol, and water up to 100 ml, specifically regarding whether the benzyl alcohol, which is currently unavailable, can be omitted or replaced with an alternative substance?
How can metronidazole be incorporated into an erythromycine solution containing zinc acetate TMF?
Regarding the prescription for 60 capsules containing 50 mg of sulpiride and 100 mg of colloidal silicon dioxide, why did the physician specify colloidal silicon dioxide, what is its added value, and considering the resulting capsules are large, can this preparation be improved by using diluent A as described in the TMF instead of silicon dioxide?
How much mannitol or NaCl should be added for the preparation of chlorhexidine eye drops 0.5%, and where can the formulas be found to calculate this?
What is a Federal Agency for Medicines and Health Products (FAMHP) approved solution for preparing Castellani solution, given that the currently used 90 percent denatured alcohol is classified as a biocide and lacks a certificate of analysis from an approved laboratory, which led to an observation during a recent FAMHP inspection of the raw materials register?
How can the instability of a cream containing 3% salicylic acid, 0.5% chlorhexidine diacetate, 5% liquor carbonis detergens (LCD), and 0.05% clobetasol propionate in an AVA base (10% Arlacel, 54% vaseline, and water) be resolved, given that the cream breaks almost instantly when the LCD is evaporated with starch and the powders are processed through a steady-state ointment mill, despite the same combination being stable in a petrolatum and paraffin base?
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